Polymyxin B sulfate ( Aerosporin; Mastimyxin )

产品货号. M11699 CAS No. 1405-20-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
1G	￥348	有现货

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产品名称

Polymyxin B sulfate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains.
产品描述

Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
同义词

Aerosporin; Mastimyxin
通路

Others
靶点

Other Targets
受体

Others
研究领域

Infection
适应症

——

CAS Number

1405-20-5
分子量

1301.56
分子式

C56H100N16O17S
纯度

>98%(HPLC)
溶解度

Water: 25 mg/mL
SMILES

CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
化学全称

N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;sulfuric acid

1.Severino P, et al. Colloids Surf B Biointerfaces. 2015 May 1;129:191-7.

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